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Signs of peritoneal irritation following gastrointestinal perforation in patients receiving corticosteroids may be minimal or absent.

Use of corticosteroids may produce posterior subcapsular cataractsglaucoma with possible damage to the optic nervesand may enhance the establishment of secondary ocular infections due to bacteriafungior virusesThe use of oral corticosteroids is not recommended in the treatment of optic neuritis and may lead to an increase in the risk of new episodesCorticosteroids should not be used in active ocular herpes simplex.

Corticosteroids can produce reversible hypothalamic-pituitary-adrenalHPAaxis suppression with the potential for corticosteroid insufficiency after withdrawal of treatmentAdrenocortical insufficiency may result from too rapid withdrawal of corticosteroids and may be minimized by gradual reduction of dosageThis type of relative insufficiency may persist for months after discontinuation of therapythereforein any situation of stress occurring during that periodhormone therapy should be reinstituted.

You develop either diseaseyou will need specialist treatment from your doctor.

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